The Deletion of GPR40/FFAR1 Signaling Damages Maternal Care and Emotional Function in Female Mice

Author:

Aizawa Fuka1,Ogaki Yoshihiro1,Kyoya Natsuki1,Nishinaka Takashi1,Nakamoto Kazuo1,Kurihara Takashi2,Hirasawa Akira3,Miyata Atsuro2,Tokuyama Shogo1

Affiliation:

1. Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Kobe Gakuin University

2. Department of Pharmacology, Graduate School of Medical and Dental Sciences, Kagoshima University

3. Department of Genomic Drug Discovery Sciences, Kyoto University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference20 articles.

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2. 2) Carlson SJ, Fallon EM, Kalish BT, Gura KM, Puder M. The role of the omega-3 fatty acid DHA in the human life cycle. JPEN J. Parenter. Enteral Nutr., 37, 15–22 (2013).

3. 3) Mossaheb N, Schloegelhofer M, Schaefer MR, Fusar-Poli P, Smesny S, McGorry P, Berger G, Amminger GP. Polyunsaturated fatty acids in emerging psychosis. Curr. Pharm. Des., 18, 576–591 (2012).

4. 4) Song C, Shieh CH, Wu YS, Kalueff A, Gaikwad S, Su KP. The role of omega-3 polyunsaturated fatty acids eicosapentaenoic and docosahexaenoic acids in the treatment of major depression and Alzheimer’s disease: Acting separately or synergistically? Prog. Lipid Res., 62, 41–54 (2016).

5. 5) Bondi CO, Taha AY, Tock JL, Totah NK, Cheon Y, Torres GE, Rapoport SI, Moghaddam B. Adolescent behavior and dopamine availability are uniquely sensitive to dietary omega-3 fatty acid deficiency. Biol. Psychiatry, 75, 38–46 (2014).

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