Design, Synthesis, and Structure–Activity Relationship Study of Epoxysuccinyl–Peptide Derivatives as Cathepsin B Inhibitors
Author:
Affiliation:
1. School of Pharmaceutical Sciences, Jilin University
2. Laboratory of Computer-Aided Drug Design & Discovery, Beijing Institute of Pharmacology and Toxicology
3. Shaanxi University of Chinese Medicine, College of Humanities and Management
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/40/8/40_b17-00075/_pdf
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4. 4) Murayama S, Imae Y, Takada K, Kikuchi J, Nakao Y, van Soest RW, Okada S, Matsunaga S. Shishicrellastatins, inhibitors of cathepsin B, from the marine sponge Crella (Yvesia) spinulata. Bioorg. Med. Chem., 19, 6594–6598 (2011).
5. 5) Matarrese P, Ascione B, Ciarlo L, Vona R, Leonetti C, Scarsella M, Mileo AM, Catricala C, Paggi MG, Malorni W. Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study. Mol. Cancer, 9, 207 (2010).
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