The Importance of Interaction with Membrane Lipids through the Pleckstrin Homology Domain of the Guanine Nucleotide Exchange Factor for Rho Family Small Guanosine Triphosphatase, FLJ00018

Author:

Kimura Shinji1,Sato Katsuya2,Banno Yoshiko3,Nagase Takahiro4,Ueda Hiroshi12

Affiliation:

1. Department of Biomolecular Science, Faculty of Engineering, Gifu University

2. The United Graduate School of Drug Discovery and Medical Information Sciences, Gifu University

3. Department of Cell Signaling, Graduate School of Medicine, Gifu University

4. Kazusa DNA Research Institute

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference18 articles.

1. 1) Etienne-Manneville S, Hall A. Rho GTPases in cell biology. Nature, 420, 629–635 (2002).

2. 2) Hall A. Rho GTPases and the actin cytoskeleton. Science, 279, 509–514 (1998).

3. 3) Aittaleb M, Boguth CA, Tesmer JJ. Structure and function of heterotrimeric G protein-regulated Rho guanine nucleotide exchange factors. Mol. Pharmacol., 77, 111–125 (2010).

4. 4) Schmidt A, Hall A. Guanine nucleotide exchange factors for Rho GTPases: turning on the switch. Genes Dev., 16, 1587–1609 (2002).

5. 5) Côté JF, Vuori K. GEF what? Dock180 and related proteins help Rac to polarize cells in new ways. Trends Cell Biol., 17, 383–393 (2007).

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