Ferulic Acid Induces Mammalian Target of Rapamycin Inactivation in Cultured Mammalian Cells

Author:

Bian Zehua1,Furuya Norihiko1,Zheng Dong-Mei1,Trejo Juan Alejandro Oliva1,Tada Norihiro2,Ezaki Junji1,Ueno Takashi1

Affiliation:

1. Department of Biochemistry, Juntendo University School of Medicine

2. Division of Genome Research, Research Institute for Diseases of Old Ages, Juntendo University School of Medicine

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference5 articles.

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3. 10) Ueno T, Sato W, Horie Y, Komatsu M, Tanida I, Yoshida M, Ohshima S, Mak TW, Watanabe S, Kominami E. Loss of Pten, a tumor suppressor, causes the strong inhibition of autophagy without affecting LC3 lipidation. Autophagy, 4, 692–700 (2008).

4. 17) Kimura S, Fujita N, Noda T, Yoshimori T. Monitoring autophagy in mammalian cultured cells through the dynamics of LC3. Methods Enzymol., 452, 1–12 (2009).

5. 23) Wang K, Liu R, Li J, Mao J, Lei Y, Wu J, Zeng J, Zhang T, Wu H, Chen L, Huang C, Wei Y. Quercetin induces protective autophagy in gastric cancer cells: involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling. Autophagy, 7, 966–978 (2011).

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