Nitric Oxide Promotes Survival of Cerebral Cortex Neurons with Simultaneous Addition of [Fe(II)(β-Citryl-L-glutamate)] Complex in Primary Culture

Author:

Hamada-Kanazawa Michiko1,Narahara Masanori1,Takano Masaoki2,Min Kyong-Son3,Tanaka Keiichi3,Miyake Masaharu1

Affiliation:

1. Department of Physiological Chemistry, Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

2. Department of Life Science Pharmacy, Faculty of Pharmaceutical Sciences, Kobe-Gakuin University

3. Laboratory of Toxicology, Faculty of Pharmacy, Osaka Ohtani University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference46 articles.

1. 1) Drapier JC, Hibbs JB Jr. Aconitases: a class of metalloproteins highly sensitive to nitric oxide synthesis. Methods Enzymol., 269, 26–36 (1996).

2. 2) Gardner PR. Aconitase: sensitive target and measure of superoxide. Methods Enzymol., 349, 9–23 (2002).

3. 3) Kennedy MC, Emptage MH, Dreyer JL, Beinert H. The role of iron in the activation–inactivation of aconitase. J. Biol. Chem., 258, 11098–11105 (1983).

4. 4) Lancaster JR Jr, Langrehr JM, Bergonia HA, Murase N, Simmons RL, Hoffman RA. EPR detection of heme and nonheme iron-containing protein nitrosylation by nitric oxide during rejection of rat heart allograft. J. Biol. Chem., 267, 10994–10998 (1992).

5. 5) Drapier JC, Hirling H, Wietzerbin J, Kaldy P, Kühn LC. Biosynthesis of nitric oxide activates iron regulatory factor in macrophages. EMBO J., 12, 3643–3649 (1993).

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