Expression and Secretion of Cholera Toxin B Subunit in Lactobacilli

Author:

Okuno Takahiro1,Kashige Nobuhiro1,Satho Tomomitsu1,Irie Keiichi1,Hiramatsu Yukihiro1,Sharmin Tanjina1,Fukumitsu Yuki1,Uyeda Saori1,Yamada Seitaro2,Harakuni Tetsuya2,Miyata Takeshi2,Arakawa Takeshi2,Imoto Masumi3,Toda Akihisa3,Nakashima Yukihiko1,Miake Fumio1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Fukuoka University

2. Molecular Microbiology Group, Department of Tropical Infectious Diseases, COMB, Tropical Biosphere Research Center, University of the Ryukyus

3. Department of Hygienic Chemistry, Daiichi University of Pharmacy

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference25 articles.

1. 1) Yigang XU, Yijing LI. Construction of recombinant Lactobacillus casei efficiently surface displayed and secreted porcine parvovirus VP2 protein and comparison of the immune responses induced by oral immunization. Immunology, 124, 68–75 (2008).

2. 2) Welman AD, Maddox IS. Exopolysaccharides from lactic acid bacteria: perspectives and challenges. Trends Biotechnol., 21, 269–274 (2003).

3. 3) del Rio B, Dattwyler RJ, Aroso M, Neves V, Meirelles L, Seegers JF, Gomes-Solecki M. Oral immunization with recombinant Lactobacillus plantarum induces a protective immune response in mice with Lyme disease. Clin. Vaccine Immunol., 15, 1429–1435 (2008).

4. 4) Jung SW, Kim WJ, Lee KG, Kim CW, Noh WS. Fermentation characteristics of exopolysaccharide-producing lactic acid bacteria from sourdough and assessment of the isolates for industrial potential. J. Microbiol. Biotechnol., 18, 1266–1273 (2008).

5. 5) Rigaux P, Daniel C, Hisbergues M, Muraille E, Hols P, Pot B, Pestel J, Jacquet A. Immunomodulatory properties of Lactobacillus plantarum and its use as a recombinant vaccine against mite allergy. Allergy, 64, 406–414 (2009).

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