A Simple and Sensitive Method for the Determination of Fibric Acids in the Liver by Liquid Chromatography

Author:

Karahashi Minako1,Fukuhara Hiroto1,Hoshina Miki1,Sakamoto Takeshi1,Yamazaki Tohru1,Mitsumoto Atsushi2,Kawashima Yoichi1,Kudo Naomi1

Affiliation:

1. Faculty of Pharmaceutical Sciences, Josai University

2. Faculty of Pharmaceutical Sciences, Josai International University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference21 articles.

1. 1) Keating GM, Croom KF. Fenofibrate: a review of its use in primary dyslipidaemia, the metabolic syndrome and type 2 diabetes mellitus. Drugs, 67, 121–153 (2007).

2. 2) Wilding JPH. PPAR agonists fot the treatment of cardiovascular disease in patients with diabetes. Diabetes Obes. Metab., 14, 973–982 (2012).

3. 3) Harano Y, Yasui K, Toyama T, Nakajima T, Mitsuyoshi H, Mimani M, Hirasawa T, Itoh Y, Okanoue T. Fenofibrate, a peroxisome proliferator-activated receptor α agonist, reduces hepatic steatosis and lipid peroxidation in fatty liver Shionogi mice with hereditary fatty liver. Liver Int., 26, 613–620 (2006).

4. 4) Inoue I, Takahashi K, Katayama S, Akabane S, Negishi K, Suzuki M, Ishii J, Kawazu S. Improvement of glucose tolerance by bezafibrate in non-obese patients with hyperlipidemia and impaired glucose tolerance. Diabetes Res. Clin. Pract., 25, 199–205 (1994).

5. 5) Berger J, Wagner JA. Physiological and therapeutic roles of peroxisome proliferator-activated receptors. Diabetes Technol. Ther., 4, 163–174 (2002).

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