Panax notoginseng Saponins Promotes Stroke Recovery by Influencing Expression of Nogo-A, NgR and p75NGF, in Vitro and in Vivo

Author:

Liu Lixing1,Zhu Lingqun1,Zou Yihuai2,Liu Wei1,Zhang Xiaoqian1,Wei Xiaoqin1,Hu Bo1,Chen Jiaxu3

Affiliation:

1. Key Laboratory of Chinese Internal Medicine of Educational Ministry and Beijing, Dongzhimen Hospital, Beijing University of Chinese Medicine

2. Department of Neurology, Dongzhimen Hospital, Beijing University of Chinese Medicine

3. Department of Chinese Medicine Diagnosis, School of Preclinical Medicine, Beijing University of Chinese Medicine

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference33 articles.

1. 1) Roger VL, Go AS, Lloyd-Jones DM, Benjamin EJ, Berry JD, Borden WB, Bravata DM, Dai S, Ford ES, Fox CS, Fullerton HJ, Gillespie C, Hailpern SM, Heit JA, Howard VJ, Kissela BM, Kittner SJ, Lackland DT, Lichtman JH, Lisabeth LD, Makuc DM, Marcus GM, Marelli A, Matchar DB, Moy CS, Mozaffarian D, Mussolino ME, Nichol G, Paynter NP, Soliman EZ, Sorlie PD, Sotoodehnia N, Turan TN, Virani SS, Wong ND, Woo D, Turner MB, American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart Disease and Stroke Statistics—2012 Update: A Report from the American Heart Association. Circulation, 125, 188–197 (2012).

2. 2) Kelly-Hayes M, Beiser A, Kase CS, Scaramucci A, D’Agostino RB, Wolf PA. The influence of gender and age on disability following ischemic stroke: the Framingham study. J. Stroke Cerebrovasc. Dis., 12, 119–126 (2003).

3. 3) Gonzenbach RR, Schwab ME. Disinhibition of neurite growth to repair the injured adult CNS: Focusing on Nogo. Cell. Mol. Life Sci., 65, 161–176 (2008).

4. 4) Quarles RH. Myelin-associated glycoprotein (MAG): past, present and beyond. J. Neurochem., 100, 1431–1448 (2007).

5. 5) Nakaya N, Sultana A, Lee HS, Tomarev SI. Olfactomedin 1 interacts with the Nogo A receptor complex to regulate axon growth. J. Biol. Chem., 287, 37171–37184 (2012).

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