Improvements of Doxorubicin-Induced Antitumor Activity and Adverse Reaction by Combined Citrulline

Author:

Miyashita Michiko1,Sadzuka Yasuyuki1

Affiliation:

1. Department of Advanced Pharmaceutics, School of Pharmacy, Iwate Medical University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference27 articles.

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2. 2) Itamochi H, Oishi T, Shimada M, Sato S, Uegaki K, Naniwa J, Sato S, Nonaka M, Terakawa N, Kigawa J, Harada T. Inhibiting the mTOR pathway synergistically enhances cytotoxicity in ovarian cancer cells induced by etoposide through upregulation of c-Jun. Clin. Cancer Res., 17, 4742–4750 (2011).

3. 3) Kubota T. The role of S-1 in the treatment of gastric cancer. Br. J. Cancer, 98, 1301–1304 (2008).

4. 4) Ozols RF, Bundy BN, Greer BE, Fowler JM, Clarke-Pearson D, Burger RA, Mannel RS, DeGeest K, Hartenbach EM, Baergen R, Gynecologic Oncology Group. Phase III trial of carboplatin and paclitaxel compared with cisplatin and paclitaxel in patients with optimally resected stage III ovarian cancer: a Gynecologic Oncology Group Study. J. Clin. Oncol., 21, 3194–3200 (2003).

5. 5) Vasey PA, Jayson GC, Gordon A, Gabra H, Coleman R, Atkinson R, Parkin D, Paul J, Hay A, Kaye SB, Scottish Gynaecological Cancer Trials Group. Phase III randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma. J. Natl. Cancer Inst., 96, 1682–1691 (2004).

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