Abnormalities in Itch Sensation and Skin Barrier Function in Atopic NC/Tnd Mice

Author:

Amagai Yosuke1,Matsuda Hiroshi12,Tanaka Akane13

Affiliation:

1. Cooperative Major in Advanced Health Science, Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology

2. Laboratory of Veterinary Molecular Pathology and Therapeutics, Tokyo University of Agriculture and Technology

3. Comparative Animal Medicine, Division of Animal Life Science, Tokyo University of Agriculture and Technology

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference25 articles.

1. 1) Johansson SGO, Hourihane JO, Bousquet J, Bruijnzeel-Koomen C, Dreborg S, Haahtela T, Kowalski ML, Mygind N, Ring J, van Cauwenberge P, van Hage-Hamsten M, Wüthrich B. Guidelines for treatment of atopic eczema (atopic dermatitis) Part I. Allergy, 56, 813–824 (2001).

2. 2) Williams HC. What is atopic dermatitis and how should it be defined in epidemiological studies? Cambridge University Press, pp. 3–24 (2000).

3. 3) Schmid-Ott G, Jaeger B, Meyer S, Stephan E, Kapp A, Werfel T. Different expression of cytokine and membrane molecules by circulating lymphocytes on acute mental stress in patients with atopic dermatitis in comparison with healthy controls. J. Allergy Clin. Immunol., 108, 455–462 (2001).

4. 4) Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, Goudie DR, Sandilands A, Campbell LE, Smith FJ, O’Regan GM, Watson RM, Cecil JE, Bale SJ, Compton JG, DiGiovanna JJ, Fleckman P, Lewis-Jones S, Arseculeratne G, Sergeant A, Munro CS, El Houate B, McElreavey K, Halkjaer LB, Bisgaard H, Mukhopadhyay S, McLean WH. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat. Genet., 38, 441–446 (2006).

5. 5) Cork MJ, Danby SG, Vasilopoulos Y, Hadgraft J, Lane ME, Moustafa M, Guy RH, Macgowan AL, Tazi-Ahnini R, Ward SJ. Epidermal barrier dysfunction in atopic dermatitis. J. Invest. Dermatol., 129, 1892–1908 (2009).

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