Electrophysiological Effects of an Anti-influenza Drug Oseltamivir on the Guinea-Pig Atrium: Comparison with Those of Pilsicainide

Author:

Takahara Akira1,Suzuki Sanae1,Hagiwara Mihoko1,Nozaki Shuhei1,Sugiyama Atsushi2

Affiliation:

1. Department of Pharmacology and Therapeutics, Faculty of Pharmaceutical Sciences, Toho University

2. Department of Pharmacology, Faculty of Medicine, Toho University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference8 articles.

1. 1) Tullu MS. Oseltamivir. J. Postgrad. Med., 55, 225–230 (2009).

2. 2) Kitahara K, Nakamura Y, Tsuneoka Y, Adachi-Akahane S, Tanaka H, Yamazaki H, Takahara A, Yamazaki J, Ikeda T, Sugiyama A. Cardiohemodynamic and electrophysiological effects of anti-influenza drug oseltamivir in vivo and in vitro. Cardiovasc. Toxicol., (2013), in press.

3. 3) Takahara A, Takeda K, Tsuneoka Y, Hagiwara M, Namekata I, Tanaka H. Electrophysiological effects of the class Ic antiarrhythmic drug pilsicainide on the guinea-pig pulmonary vein myocardium. J. Pharmacol. Sci., 118, 506–511 (2012).

4. 4) Takahara A, Takeda K, Hagiwara M, Tanaka H. Electrophysiological effects of the antiarrhythmic drug bepridil on the guinea-pig pulmonary vein myocardium. Biol. Pharm. Bull., 36, 311–315 (2013).

5. 5) Chugai Pharmaceutical Co., Ltd., F. Hoffmann-La Roche Ltd. Non-clinical studies conducted by order of the basic working group and results of voluntary examination and analysis (No. 2). P47-57, December 10, 2007. The 4th working group for basic research and examination of oseltamivir phosphate. (in Japanese): ‹http://www.mhlw.go.jp/shingi/2007/12/s1210-6.html›, cited 12 July, 2013.

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