Involvement of Hepatic IL-1 in the Strain-Dependent Sex Differences in Serum Total Cholesterol Levels in Rats

Author:

Kumagai Yoichi12,Sekimoto Masashi1,Okamoto Minako2,Kurita Ryuzo1,Kojima Misaki3,Degawa Masakuni1

Affiliation:

1. Department of Molecular Toxicology, School of Pharmaceutical Sciences, University of Shizuoka

2. Pharmacokinetics and Safety Research Department, Central Research Laboratories, Kaken Pharmaceutical Co., Ltd.

3. Animal Genome Research Unit, Agrogenomics Research Center, National Institute of Agrobiological Sciences

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference21 articles.

1. 1) Goldstein JL, Brown MS. Regulation of the mevalonate pathway. Nature, 343, 425–430 (1990).

2. 2) Chiang JYL. Regulation of bile acid synthesis. Front. Biosci., 3, d176–d193 (1998).

3. 3) Russell DW. Nuclear orphan receptors control cholesterol catabolism. Cell, 97, 539–542 (1999).

4. 4) Farhat MY, Lavigne MC, Ramwell PW. The vascular protective effects of estrogen. FASEB J., 10, 615–624 (1996).

5. 5) Knowlton AA, Lee AR. Estrogen and the cardiovascular system. Pharmacol. Ther., 135, 54–70 (2012).

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