Sesamin Induces Cell Cycle Arrest and Apoptosis through the Inhibition of Signal Transducer and Activator of Transcription 3 Signalling in Human Hepatocellular Carcinoma Cell Line HepG2

Author:

Deng Pengyi1,Wang Chen1,Chen Liulin1,Wang Cheng1,Du Yuhan1,Yan Xu1,Chen Mingjie1,Yang Guangxiao1,He Guangyuan1

Affiliation:

1. The Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science & Technology (HUST)

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference35 articles.

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2. 2) Bollrath J, Phesse TJ, Von Burstin VA, Putoczki T, Bennecke M, Bateman T, Nebelsiek T, Lundgren-May T, Canli O, Schwitalla S, Matthews V, Schmid RM, Kirchner T, Arkan MC, Ernst M, Greten FR. gp130-mediated STAT3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell, 15, 91–102 (2009).

3. 3) Yu H, Jove R. The STATs of cancer - New molecular targets come of age. Nat. Rev. Cancer, 4, 97–105 (2004).

4. 4) Darnell JE Jr. STATs and gene regulation. Science, 277, 1630–1635 (1997).

5. 5) Reich NC, Liu L. Tracking STAT nuclear traffic. Nat. Rev. Immunol., 6, 602–612 (2006).

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