Therapeutic Effects of Gel Ointments Containing Tranilast Nanoparticles on Paw Edema in Adjuvant-Induced Arthritis Rats

Author:

Nagai Noriaki1,Ito Yoshimasa1

Affiliation:

1. School of Pharmacy, Kinki University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference52 articles.

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2. 2) Bombini G, Canetti C, Rocha FAC, Cunha FQ. Tumour necrosis factor-alpha mediates neutrophil migration to the knee synovial cavity during immune inflammation. Eur. J. Pharmacol., 496, 197–204 (2004).

3. 3) Skapenko A, Leipe J, Lipsky PE, Schulze-Koops H. The role of the T cell in autoimmune inflammation. Arthritis Res. Ther., 7 (Suppl. 2), S4–S14 (2005).

4. 4) Park CS, Lim H, Han KJ, Baek SH, Sohn HO, Lee DW, Kim YG, Yun HY, Baek KJ, Kwon NS. Inhibition of nitric oxide generation by 23,24-dihydrocucurbitacin D in mouse peritoneal macrophages. J. Pharmacol. Exp. Ther., 309, 705–710 (2004).

5. 5) Park HJ, Lee SH, Son DJ, Oh KW, Kim KH, Song HS, Kim GJ, Oh GT, Yoon DY, Hong JT. Antiarthritic effect of bee venom: inhibition of inflammation mediator generation by suppression of NF-κB through interaction with the p50 subunit. Arthritis Rheum., 50, 3504–3515 (2004).

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