3,3′,4,4′-Tetrachlorobiphenyl-Mediated Decrease of Serum Thyroxine Level in C57BL/6 and DBA/2 Mice Occurs Mainly through Enhanced Accumulation of Thyroxine in the Liver

Author:

Kato Yoshihisa1,Haraguchi Koichi2,Onishi Mao3,Ikushiro Shinichi4,Endo Tetsuya5,Ohta Chiho6,Koga Nobuyuki6,Yamada Shizuo3,Degawa Masakuni3

Affiliation:

1. Kagawa School of Pharmaceutical Sciences, Tokushima Bunri University

2. Daiichi College of Pharmaceutical Sciences

3. School of Pharmaceutical Sciences, University of Shizuoka

4. Faculty of Engineering, Toyama Prefectural University

5. Faculty of Pharmaceutical Sciences, Health Sciences University of Hokkaido

6. Faculty of Nutritional Sciences, Nakamura Gakuen University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Reference28 articles.

1. 1) PCBs: Recent advances in environmental toxicology and health effects. (Robertson LW, Hansen LG. ed.) University Press of Kentucky, Kentucky, pp. 1–461 (2001).

2. 2) Kuratsune M, Yoshimura H, Matsuzaka J, Yamaguchi A. Epidemiologic study on Yusho, a poisoning caused by ingestion of rice oil contaminated with a commercial brand of polychlorinated biphenyls. Environ. Health Perspect., 1, 119–128 (1972).

3. 3) WHO-IPCS. Polychlorinated Biphenyls and Terphenyls. Environmental Health Criteria Series, No. 140, World Health Organization, Geneva, pp. 1–682 (1993).

4. 4) Masuda Y. Toxic effects of PCB/PCDF to human observed in Yusho and other poisonings. Fukuoka Igaku Zasshi, 100, 141–155 (2009).

5. 5) Seo BW, Li MH, Hansen LG, Moore RW, Peterson RE, Schantz SL. Effects of gestational and lactational exposure to coplanar polychlorinated biphenyl (PCB) congeners or 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on thyroid hormone concentrations in weanling rats. Toxicol. Lett., 78, 253–262 (1995).

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