The Anti-overactive Bladder Activity of KW-7158 Is Mediated by Blocking Equilibrative Nucleoside Transporter-1-Reference-Cited by-同舟云学术

The Anti-overactive Bladder Activity of KW-7158 Is Mediated by Blocking Equilibrative Nucleoside Transporter-1

Published:2014 Issue:1 Volume:37 Page:130-136
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Nishiya Yoichi¹,Yamagata Tsuyoshi²,Fukuda Ayumu¹,Yokokawa Sachiko¹,Seishi Takashi³,Sakuma Takashi³,Sasho Setsuya³,Shimizu Yukiko¹,Sato Hidetaka¹,Sekine Susumu¹,Kamigaki Masayo¹,Yoshida Tetsuo¹,Shibata Kenji¹

Affiliation:

1. Biologics Research Laboratories, Kyowa Hakko Kirin Co., Ltd.

2. Pharmacological Research Laboratories, Kyowa Hakko Kirin Co., Ltd.

3. Medicinal Chemistry Research Laboratories, Kyowa Hakko Kirin Co., Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/37/1/37_b13-00658/_pdf

Reference29 articles.

1. 1) Yamagata T, Atsuki K, Ohno T, Shirakura S, de Groat WC, Sculporeanu A, Karasawa A, Yoshimura N. Agent for the treatment of overactive bladder. International Patent Application WO02/078523 (2002).

2. 2) Yamagata T, Atsuki K, Ohno T, Shirakura S, de Groat WC, Yoshimura N, Sculporeanu A, Karasawa A. Agent for the treatment of bladder irritative symptoms accompanied by benign prostatic hyperplasia. International Patent Application WO02/078633 (2002).

3. 3) Yoshida M, Seishi T, Aono S, Takai H, Suzuki K, Yamagata T, Atsuki K, Karasawa A, Kumazawa T. Tricyclic Compounds. International Patent Application WO98/046587 (1998).

4. 4) Lu SH, Yamagata T, Atsuki K, Sun L, Smith CP, Yoshimura N, Chancellor MB, de Groat WC. Effect of KW-7158, a putative afferent nerve inhibitor, on bladder and vesico-vascular reflexes in rats. Brain Res., 946, 72–78 (2002).

5. 5) Sculptoreanu A, Yoshimura N, de Groat WC. KW-7158 [(2S)-(+)-3,3,3-trifluoro-2-hydroxy-2-methyl-N-(5,5,10-trioxo-4,10-dihydrothieno[3,2-c][1]benzothiepin-9-yl)propanamide] enhances A-type K+ currents in neurons of the dorsal root ganglion of the adult rat. J. Pharmacol. Exp. Ther., 310, 159–168 (2004).

Cited by 3 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Applications of proteomics in pharmaceutical research and development;Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics;2019-01

3. Therapeutic targets for overactive bladder other than smooth muscle;Expert Opinion on Therapeutic Targets;2015-02-23