Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. III. Synthesis and Antitumor Activity of 3-Phenylpiperazinyl-1-trans-propenes-Reference-Cited by-同舟云学术

Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. III. Synthesis and Antitumor Activity of 3-Phenylpiperazinyl-1-trans-propenes

Published:2005 Issue:2 Volume:53 Page:153-163
ISSN:0009-2363
Container-title:Chemical and Pharmaceutical Bulletin
language:en
Short-container-title:CHEMICAL & PHARMACEUTICAL BULLETIN

Author:

Naito Hiroyuki¹,Ohsuki Satoru¹,Atsumi Ryo²,Minami Megumi³,Mochizuki Mineko³,Hirotani Kenji⁴,Kumazawa Eiji³,Ejima Akio¹

Affiliation:

1. Medicinal Chemistry Research Laboratory, Daiichi Pharmaceutical Co. Ltd.

2. Drug Metabolism & Physicochemical Property Research Laboratory, Daiichi Pharmaceutical Co. Ltd.

3. New Product Research Laboratories III, Daiichi Pharmaceutical Co. Ltd.

4. Discovery Research Laboratory, Daiichi Pharmaceutical Co. Ltd.

Publisher

Pharmaceutical Society of Japan

Subject

Drug Discovery,General Chemistry,General Medicine

Link

http://www.jstage.jst.go.jp/article/cpb/53/2/53_2_153/_pdf

Reference22 articles.

1. Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives.

2. Synthesis and Antitumor Activity of Novel Pyrimidinyl Pyrazole Derivatives. II. Optimization of the Phenylpiperazine Moiety of 1-[5-Methyl-1-(2-pyrimidinyl)-4-pyrazolyl]-3-phenylpiperazinyl-1-trans-propenes.

3. 3) Compounds 5a, b, e, f, g, and i were commercially available.

4. Synthesis and evaluation of the thiosemicarbazone, dithiocarbazonate, and 2'-pyrazinylhydrazone of pyrazinecarboxaldehyde as agents for the treatment of iron overload

5. Radicals derived from heteroaromatic systems. II. Thiazolyl radicals

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