Discovery of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors with a 1<i>H</i>-Pyrrolo[2,3-<i>b</i>]pyridine Core-Reference-Cited by-同舟云学术

Discovery of a Novel Class of Diacylglycerol Acyltransferase 2 Inhibitors with a 1H-Pyrrolo[2,3-b]pyridine Core

Published:2014 Issue:10 Volume:37 Page:1655-1660
ISSN:0918-6158
Container-title:Biological and Pharmaceutical Bulletin
language:en
Short-container-title:Biol. Pharm. Bull.

Author:

Kim Mun Ock¹,Lee Suui¹,Choi Kwangman¹,Lee Sangku¹,Kim Hyeongki¹²,Kang Hyunju¹,Choi Miri¹,Kwon Eun Bin¹,Kang Myung Ji¹,Kim Sunhong¹²,Lee Hyun-Jun¹,Lee Hyun Sun¹,Kwak Young-Shin³,Cho Sungchan¹²

Affiliation:

1. Targeted Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology

2. Department of Biomolecular Science, University of Science and Technology

3. College of Pharmacy, Korea University

Publisher

Pharmaceutical Society of Japan

Subject

Pharmaceutical Science,Pharmacology,General Medicine

Link

https://www.jstage.jst.go.jp/article/bpb/37/10/37_b14-00447/_pdf

Reference22 articles.

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3. 3) Nagle CA, Klett EL, Coleman RA. Hepatic triacylglycerol accumulation and insulin resistance. J. Lipid Res., 50 (Suppl.), S74–S79 (2008).

4. 4) Tziomalos K, Athyros VG, Karagiannis A, Kolovou GD, Mikhailidis DP. Triglycerides and vascular risk: insights from epidemiological data and interventional studies. Curr. Drug Targets, 10, 320–327 (2009).

5. 5) Turchetto-Zolet AC, Maraschin FS, de Morais GL, Cagliari A, Andrade CM, Margis-Pinheiro M, Margis R. Evolutionary view of acyl-CoA diacylglycerol acyltransferase (DGAT), a key enzyme in neutral lipid biosynthesis. BMC Evol. Biol., 11, 263 (2011).

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