In Vitro Inhibition of CYP2C9-Mediated Warfarin 7-Hydroxylation by Iguratimod
Author:
Affiliation:
1. Department of Pharmacy, Shinshu University Hospital
2. Department of Biochemical Pharmacology and Toxicology, Graduate School of Medicine, Shinshu University
3. School of Medicine, Shinshu University
Publisher
Pharmaceutical Society of Japan
Subject
Pharmaceutical Science,Pharmacology,General Medicine
Link
https://www.jstage.jst.go.jp/article/bpb/38/3/38_b14-00711/_pdf
Reference20 articles.
1. 1) Ishiguro N, Yamamoto K, Katayama K, Kondo M, Sumida T, Mimori T, Soen S, Nagai K, Yamaguchi T, Hara M, Iguratimod-Clinical Study Group. Concomitant iguratimod therapy in patients with active rheumatoid arthritis despite stable doses of methotrexate: a randomized, double-blind, placebo-controlled trial. Mod. Rheumatol., 23, 430–439 (2013).
2. 2) Hara M, Ishiguro N, Katayama K, Kondo M, Sumida T, Mimori T, Soen S, Nagai K, Yamaguchi T, Yamamoto K, Iguratimod-Clinical Study Group. Safety and efficacy of combination therapy of iguratimod with methotrexate for patients with active rheumatoid arthritis with an inadequate response to methotrexate: an open-label extension of a randomized, double-blind, placebo-controlled trial. Mod. Rheumatol., 24, 410–418 (2014).
3. 3) Taisho Toyama Pharmaceutical Co., Ltd., Japan. Interview Form (KOLBET® Tablets 25 mg), 6th edition (2013).
4. 4) Ministry of Health, Labour, and Welfare, Japan. “Careram® Tablets 25mg; KOLBET® Tablets 25mg (Iguratimod)-Risk of severe haemorrhages by a suspected interaction with warfarin.”: ‹http://www.pmda.go.jp/english/service/pdf/letter/130517-iguratimod.pdf›, cited 25 September, 2014.
5. 5) O’Reilly RA. Studies on the optical enantiomorphs of warfarin in man. Clin. Pharmacol. Ther., 16, 348–354 (1974).
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