EFFECT OF ENTAMOEBA HISTOLYTIC TO THE IMMUNE CHEMOKINES IN SAMARRA CITY

Abstract

The current study aimed to reveal the evaluation of the level of some immune chemokines and liver function in infected with the parasite Entamoeba Histolytica. , Blood samples were collected during the period from the beginning of August 2021 until the month of April 2022. The separated sera were kept at -20 temperature until use. Enzyme-linked immunosorbent adsorption (ELISA) technique was used to detect dysentery amoeba infection. CCR2 and CCL2 levels were measured using ELISA technique, while ALP, ALT, AST and TSP were measured using Spectophotomertric method. In the current study, 250 samples were taken, and the number of samples infected with the dysentery amoeba parasite was 120 samples, at a rate of 48%,  The results of the current study showed a significant increase of P≤0.05, as it was found that there were significant differences in the group with diarrhea only without the presence of the dysentery amoeba parasite, where there was an increase in the levels of ALT, AST, ALP and globulin compared to the control group. It was also found that there were no significant differences in AST levels between the group infected with the dysentery amoeba parasite compared to the control group.