Exploring how lifestyle choices influence the management of chronic diseases-role of healthcare providers
-
Published:2021-01-15
Issue:S1
Volume:5
Page:1100-1128
-
ISSN:2550-696X
-
Container-title:International journal of health sciences
-
language:
-
Short-container-title:Int. J. of Health Sci.
Author:
Alotaibi Fahdah Mehsan,Almazam Abdulrhman Ali,Alotaibi Motaeb,Emam Arwa Mohammad,Alqahtani Naif Saad,Alheggi Ashwaq Ibrahim,Alanazi Ashwaq Fahad,Alharbi Khlood Khaldan,Alhamed Arwa Abdullah,Ali Eman Ibrahim Alshaikh,Alnemer Maram Jaafar,Alghamdi Mahfoudh Saad,Alomayrah Norah Mubarak,Alsharari Abdulaziz Shaem,Alsharari Sami Farhan,Alshamari Moteb Roshaid,Lamfon Nahid Ahmad,Al-Qahtani Asma Saad
Abstract
Background: Chronic diseases are increasingly prevalent worldwide, with lifestyle choices playing a significant role in their management. Free radicals and oxidative stress have been implicated in various chronic conditions, including cardiovascular diseases, cancer, and neurodegenerative disorders. These conditions arise from an imbalance between reactive oxygen species (ROS) production and the body's antioxidant defenses. Aim: This review aims to explore how lifestyle choices influence oxidative stress and chronic disease management, with a focus on the role of healthcare providers in guiding lifestyle modifications to mitigate oxidative stress and improve health outcomes. Methods: A comprehensive review of the literature was conducted, focusing on the mechanisms of oxidative stress and its impact on chronic diseases. Studies on the effects of lifestyle factors such as diet, exercise, smoking, and alcohol consumption on oxidative stress were analyzed. The role of antioxidants in counteracting oxidative damage and their implications for chronic disease management were also examined. Results: The review highlights that lifestyle factors significantly affect oxidative stress levels. Moderate exercise enhances antioxidant defenses, while excessive physical activity, smoking, and alcohol consumption exacerbate oxidative stress. A diet rich in antioxidants helps mitigate oxidative damage.
Publisher
Universidad Tecnica de Manabi
Reference204 articles.
1. Abramov, A. Y., Jacobson, J., Wientjes, F., Hothersall, J., Canevari, L., and Duchen, M. R. (2005). Expression and modulation of an NADPH oxidase in mammalian astrocytes. J. Neurosci. 25, 9176–9184. doi: 10.1523/jneurosci.1632-05.2005 2. Alfonso-Prieto, M., Biarnes, X., Vidossich, P., and Rovira, C. (2009). The molecular mechanism of the catalase reaction. J. Am. Chem. Soc. 131, 11751–11761. doi: 10.1021/ja9018572 3. Aminjan, H. H., Abtahi, S. R., Hazrati, E., Chamanara, M., Jalili, M., and Paknejad, B. (2019). Targeting of oxidative stress and inflammation through ROS/NF-kappaB pathway in phosphine-induced hepatotoxicity mitigation. Life Sci. 232:116607. doi: 10.1016/j.lfs.2019.116607 4. Andreyev, A. Y., Kushnareva, Y. E., and Starkov, A. A. (2005). Mitochondrial metabolism of reactive oxygen species. Biochemistry 70, 200–214 5. Antonioni, A., Fantini, C., Dimauro, I., and Caporossi, D. (2019). Redox homeostasis in sport: do athletes really need antioxidant support? Res. Sports Med. 27, 147–165. doi: 10.1080/15438627.2018.1563899
|
|