Assessment of effects of antihypertensive agents on the quality of life in diabetic hypertensive patients

Abstract

Background: Hypertension affects a significant number of population and many of these affected individuals have no symptoms. The present study was conducted to assess effects of antihypertensive agents on the quality of life in diabetic hypertensive patients. Materials & Methods: 96 diabetic hypertensive patients of both genders were randomly divided into 4 groups based on antihypertensive medicines- group I comprises those taking amlodipine (2.5–10 mg/day), group II taking ramipril (2.5–10 mg/day), group III taking telmisartan (40–80 mg/day) and group IV taking combination of ramipril (1.25–5 mg/day) and telmisartan (20–40 mg/day) (RT). Parameters such as blood pressure (BP), pulse rate, blood sugar level, glycated hemoglobin (HbA1c) and QOLID-Punjabi version (PV) questionnaire at baseline and then at the 24th week of therapy. QoL of the patients was assessed by using the QOLID questionnaire Results: Group I had 12 males and 12 females, group II had 14 males and 10 females, group III had 15 males and 9 females and group IV had 10 males and 14 females.