Comparative study of endoscopic rapid urease test with serology of helicobacter pylori infection in acid peptic disease

Author:

Kulkarni Deepthi Pradeep Patil,Sreeramulu P. N.,Natrajan Arvind,Srinivasa D.,Kumar Yadamreddy Rohit

Abstract

Acid Peptic Disease (APD) is worldwide health issue for the surgeons, mainly due to risk and associated complications like Gastric Ulcer (GU), Duodenal Ulcer (DU), Gastro intestinal tract (GIT) perforation. This aims at early detection of disease which is caused by Helicobacter Pylori (HP) and intervention prevents the further complications. This study is Cohort study was conducted in the endoscopic unit of Department of General Surgery Tertiary care teaching Hospital over a period of 1 year with a sample size of 121. All the patients suitable for the study in regards to the inclusion and exclusion criteria are subjected to both the study until the sample size is achieved, with the prior agreement of the institutional ethical committee. All the participants are tested with RUT and ELISA and 87.60% had RUT positive and 86.78% had ELISA positive infection. RUT had sensitivity of 87.62% in predicting ELISA, specificity was 12.50%, with a total diagnostic accuracy of 77.69%.  We treated 51.24% with the CMO kit and 48.76% with HP kit.  O

Publisher

Universidad Tecnica de Manabi

Subject

Education,General Nursing

Reference21 articles.

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