Author:
Neha Munot,Suraj Patil,Abhinandan Patil,Neeta Rai,Ujjwala Kandekar,Shweta Ghodake
Abstract
The present study was evaluated to screen the antidepressant potential of Madhuca longifolia in different animal models like forced swim test (FST), tail suspension test(TST), reserpine induced hypothermia (RIH). Adult swiss albino mice weighing 25- 30 gm.Standard drug used in above study was Fluoxetine(10mg/kg,p.o). The antidepressant activity of Madhuca longifolia was compared to the standard drug. The model shows closely mimics symptoms & signs of human depression. The high dose of Madhuca longifolia showed extremely high significant values over standard drugs with a decrease in immobility and ptosis. The results obtained in the present study suggest that Madhuca longifolia proves to be a potential therapeutic drug for treating depression along with anti-inflammatory, anti-psoriatic and antioxidant activity.
Publisher
Universidad Tecnica de Manabi
Subject
Education,General Nursing
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