Pharmacological applications of diacerein

Author:

Roy Tathagata,Chowdhury Rishta Roy,Chakraborty Payel,Dey Subhendu,Chatterjee Tapan Kumar

Abstract

IL-1β is one of the important IL-1 superfamily cytokines that shows crucial role in the pathogenesis of various inflammatory disorders like osteoarthritis, epidermolysis bullosa, psoriasis and type II diabetes. Dugs with IL-1βinhibitory effect can show promising results in these types of inflammatory disorders. Diacerein and its active metabolite rhein prevent the generation of active IL-1 and are consequently used to treat inflammatory conditions such as osteoarthritis, epidermolysis bullosa, psoriasis, and Type II diabetes.

Publisher

Universidad Tecnica de Manabi

Subject

Education,General Nursing

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