Clinical and dosimetric comparison of acute bowel toxicities in carcinoma rectum patients receiving neoadjuvant chemoradiotherapy by using standard 3DCRT VS IMRT

Abstract

Introduction: Colorectal cancer (CRC) is a common cancer worldwide. It is the third most commonly diagnosed cancer in males and the second in females, with more than 1.4 million new cancer cases every year. Around 40,000 people will be effected by rectal cancer for every year, with a 65% survival rate from past 5-year were estimated. The age standardized rate (ASR) for CRC in India is low at 7.2 per 100,000 population in males and 5.1 per 100,000 populations in women. However overall incidence and survival rates were increased due to the screening and early detection. Materials and Methods: The proposed study is a prospective, hospital based, comparative cohort study including the cases admitted to Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana with clinical features and investigations suggestive of carcinoma rectum and fulfilling the inclusion criteria will be taken up for study. Patients considered as per inclusion criteria admitted in Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana were selected and the dosimetric data was collected from the TPS planning system and clinically relevant data was collected from the patient’s record from hospital digital interface system.