Targeting RSK2 in human malignancies
Author:
Publisher
Informa Healthcare
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/14728222.2010.531013
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1. A Xenopus ribosomal protein S6 kinase has two apparent kinase domains that are each similar to distinct protein kinases.
2. Evidence for two catalytically active kinase domains in pp90rsk
3. Insulin-stimulated MAP-2 kinase phosphorylates and activates ribosomal protein S6 kinase II
4. Signal transduction via the MAP kinases: proceed at your own RSK.
5. Role and regulation of 90 kDa ribosomal S6 kinase (RSK) in signal transduction
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