Can intervention in inositol phosphate signalling pathways improve therapy for cystic fibrosis?
Author:
Publisher
Informa Healthcare
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/14728222.9.6.1307
Reference60 articles.
1. New concepts of the pathogenesis of cystic fibrosis lung disease
2. Evidence for reduced Cl- and increased Na+ permeability in cystic fibrosis human primary cell cultures.
3. ENaC is inhibited by an increase in the intracellular Cl– concentration mediated through activation of Cl– channels
4. Cl– Interference with the Epithelial Na+ Channel ENaC
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3. INO-4995 Therapeutic Efficacy Is Enhanced with Repeat Dosing in Cystic Fibrosis Knockout Mice and Human Epithelia;American Journal of Respiratory Cell and Molecular Biology;2010-01
4. Automated Potentiometric Titrations in KCl/Water-Saturated Octanol: Method for Quantifying Factors Influencing Ion-Pair Partitioning;Analytical Chemistry;2009-03-05
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