Update on the status of DP2 receptor antagonists; from proof of concept through clinical failures to promising new drugs
Author:
Affiliation:
1. Norman Consulting, 18 Pink Lane, Burnham, Bucks, SL1 8JW, UK
Publisher
Informa Healthcare
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1517/13543784.2013.839658
Reference54 articles.
1. Characterization of the reaction sequence involved in phospholipid labeling and deacylation and prostaglandin synthesis and actions
2. Spectrum of Prostanoid Release after Bronchoalveolar Allergen Challenge in Atopic Asthmatics and in Control Groups: An Alteration in the Ratio of Bronchoconstrictive to Bronchoprotective Mediators
3. International Union of Basic and Clinical Pharmacology. LXXXIII: Classification of Prostanoid Receptors, Updating 15 Years of Progress
4. The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist
5. Characterisation of receptors mediating the contractile effects of prostanoids in guinea-pig and human airways
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