Surgical treatment of atrial fibrillation with argon-based cryotechnology

Author:

Doll Nicolas1,Fabricius Alexander Max1,Meyer Ralf2,Walther Thomas1,Rastan Ardawan1,Mohr Friedrich Wilhelm1

Affiliation:

1. University of Leipzig, Clinic for Heart Surgery, Heart Center, Strümpellstraße 39 04289 Leipzig, Germany.

2. CryoCath Technologies, Inc., Quebec, Canada.

Abstract

Over the past several years numerous attempts have been made to treat atrial fibrillation surgically. The most effective of all such surgical treatments has been the Maze operation, developed by James Cox in the 1980s. The Maze operation has demonstrated excellent long-term results. The procedure is based on a complex surgical technique, thus is it not easily being reproduced by every surgeon. Different attempts have been made to simplify the original Maze technique. In 1999, the electrophysiologists at the authors’ institution outlined a lesion concept for left atrial ablation in the treatment of atrial fibrillation. In 387 patients, the authors used intraoperative radiofrequency ablation to cure AF. The results were comparable to the maze procedure. This concept was very effective but after a time period of 4 years in 1% of patients esophagus perforations occurred. In a quest to identify other energy sources to produce good ablation results with less possible complications, intraoperative cryoablation has been developed. In the following study conducted the authors were able to use a new flexible cryocatheter (Cryocath Surgifrost®). Sinus rhythm was achieved in 71% after a 1 year follow-up period with low morbidity and comparable mortality, which was due to the concomitant cardiac pathologies and operative procedures. In conclusion, thus far from this series of patients presented, the authors have demonstrated that cryoablation with Argon-cryotechnology is efficacious and safe.

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Minimally Invasive Stand-Alone Cox Maze Procedure for Persistent and Long-Standing Persistent Atrial Fibrillation;Circulation: Arrhythmia and Electrophysiology;2017-11

2. Correcting Arrhythmias: Interventional and Surgical Ablation Therapy;The Thoracic and Cardiovascular Surgeon;2017-04-07

3. Surgical Therapy of Atrial Fibrillation;Cardiology Research and Practice;2012

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