Predictive ADME-Tox
Author:
Publisher
Informa Healthcare
Subject
Pharmacology,Toxicology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/17425255.1.3.565
Reference20 articles.
1. ADMET in silico modelling: towards prediction paradise?
2. An in vivo and in vitro comparison of CYP induction in rat liver and intestine using slices and quantitative RT-PCR
3. Cytotoxic effects of 100 reference compounds on Hep G2 and HeLa cells and of 60 compounds on ECC-1 and CHO cells. I Mechanistic assays on ROS, glutathione depletion and calcein uptake
4. Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells.
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2. The value of in silico chemistry in the safety assessment of chemicals in the consumer goods and pharmaceutical industries;Drug Discovery Today;2012-02
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4. Considerations and recent advances in QSAR models for cytochrome P450-mediated drug metabolism prediction;Journal of Computer-Aided Molecular Design;2008-06-24
5. Pharmacokinetics in Drug Discovery;Journal of Pharmaceutical Sciences;2008-02
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