Pharmacokinetics and pharmacodynamics of MD1003 (high-dose biotin) in the treatment of progressive multiple sclerosis

Author:

Peyro Saint Paul Laure1,Debruyne Danièle2,Bernard Delphine3,Mock Donald M.4,Defer Gilles L.56

Affiliation:

1. Clinical Research, Centre Hospitalier Universitaire de Caen, Caen, France

2. Pharmacology, Centre Hospitalier Universitaire de Caen, Caen, France

3. MedDay Pharmaceuticals, ICM-Brain and Spine Institute-IPEPs, Groupe Hospitalier Pitié Salpêtrière, Paris, France

4. Department of Biochemistry & Molecular Biology and Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA

5. Neurology, Centre Hospitalier Universitaire de Caen, Caen, France

6. INSERM U 919, GIP Cyceron, Caen, France

Publisher

Informa Healthcare

Subject

Pharmacology,Toxicology,General Medicine

Reference114 articles.

1. Multiple Sclerosis International Federation (MSIF). Atlas of MS 2013. Mapping multiple sclerosis around the world; 2013.

2. Natural history of multiple sclerosis: a unifying concept

3. Defining the clinical course of multiple sclerosis: The 2013 revisions

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