Rationalization and prediction ofin vivometabolite exposures: the role of metabolite kinetics, clearance predictions andin vitroparameters
Author:
Publisher
Informa Healthcare
Subject
Pharmacology,Toxicology,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1517/17425255.2010.497487
Reference119 articles.
1. Benzodiazepines in epilepsy: pharmacology and pharmacokinetics
2. Effects of antidepressants on intracellular Ca2+ mobilization in CHO cells transfected with the human 5-HT2C receptors
3. Valproic Acid-Induced Carbamazepine-10,11-Epoxide Toxicity in Children and Adolescents
4. Influence of CYP2C9 genotypes on the formation of a hepatotoxic metabolite of valproic acid in human liver microsomes
5. Comparison of the Bioactivation Potential of the Antidepressant and Hepatotoxin Nefazodone with Aripiprazole, a Structural Analog and Marketed Drug
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