Pharmacokinetics and concentration–effect relationships of therapeutic monoclonal antibodies and fusion proteins
Author:
Affiliation:
1. François-Rabelais University, UPRES EA 3853 ‘Immuno-Pharmaco-Genetics of Therapeutic Antibodies’, Faculty of Medicine, 2 bis Boulevard Tonnellé, B.P. 3223, F 37032 Tours Cedex 1, France.
Publisher
Informa Healthcare
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology
Link
https://www.tandfonline.com/doi/pdf/10.1517/14712598.5.1.S37
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3. KHAZAELI MB, SALEH MN, LIU TP et al.: Pharmacokinetics and immune response of 131I-chimeric mouse/human B72.3 (human gamma 4) monoclonal antibody in humans. Cancer Res. (1991) 51(20):5461–5466.
4. BREED VELD FC: Therapeutic monoclonal antibodies. Lancet (2000) 355(9205):735–740. OWEN CE: Anti-immunoglobulin E therapy for asthma. Pulm. Pharmacol Ther. (2002) 15(5):417–424. VAISHNAW AK, TENHOOR CN: Pharmacokinetics, biologic activity, and tolerability of alefacept by intravenous and intramuscular administration. Pharmacokinet. Pharmacodyn. (2002) 29(5–6):415–426.
5. ECONOMIDES AN, CARPENTER LR, RUDGE JS et al.: Cytokine traps: multicomponent, high-affinity blockers of cytokine action. Nat. Med. (2003 (1):47–52.
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