Evolving role of rituximab in the treatment of patients with non-Hodgkin's lymphoma-Reference-Cited by-同舟云学术

Evolving role of rituximab in the treatment of patients with non-Hodgkin's lymphoma

Published:2005-06 Issue:3 Volume:1 Page:297-306
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Coiffier Bertrand B¹,Traullé Catherine²

Affiliation:

1. Hospices Civils de Lyon and Université Claude Bernard, Lyon Hematology Department, CH Lyon-Sud 69495 Pierre Benite, France.

2. Hospices Civils de Lyon, Hematology Department, CH Lyon-Sud, 69495 Pierre-Benite, France.

Abstract

Rituximab is the first monoclonal antibody to have been registered for the treatment of B-cell lymphomas. Randomized studies have demonstrated its activity in follicular lymphoma, mantle cell lymphoma, and diffuse large B-cell lymphoma in untreated or relapsing patients. Rituximab has transformed the outcome of these patients because of its high activity and low toxicity. A combination of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone, has the highest efficacy ever described with any chemotherapy in diffuse large B-cell lymphoma and follicular lymphoma.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.1517/14796694.1.3.297

Reference64 articles.

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4. Expression of complement inhibitors CD46, CD55, and CD59 on tumor cells does not predict clinical outcome after rituximab treatment in follicular non-Hodgkin lymphoma

5. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

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