Intestinal necrosis due to mesenteric ischemia in COVID-19 patients. Reviewing 3 patients have been treated at Cho Ray University Hospital

Abstract

Abstract Introduction: The Covid-19 pandemic has resulted in severe complications and even death in many patients globally. Beside the most common impairments in the lung, SARS-CoV-2 infection-related hypercoagulation is not rarely seen in outpatients as well as in hospitalized patients. Such adverse event could engender vascular embolism in various viscera. During the Covid-19 outbreak in the years of 2020-2022, there have been several post-Covid-19 cases with bowel necrosis due to mesenteric ischemia which were well recorded worldwide. The impact of Covid-19 infection and mesenteric ischemia should be investigated. Patients and methods: We reported three young patients aged less than 40 years old who were diagnosed with bowel necrosis after Covid-19 infection at our center. Clinical, paraclinical manifestations, computed tomography features, diagnosis, treatment and final outcomes were recorded. Results: All three patients had mesenteric ischemia which caused intestinal necrosis in some extents. The patients underwent bowel resection with temporary stoma. Postoperative anticoagulant administration, nutritional support and delayed bowel reconstruction were performed with good outcomes. Conclusion: Understanding the impact of Covid-19 infection on mesenteric vascular helps to prevent, early detect the occurrence of bowel necrosis and effectively treat this complication. Keywords: Covid-19, SARS-CoV-2, mesenteric ischemia, bowel necrosis, compensation of bowel fluid.