Affiliation:
1. Volgograd State Medical University; Volgograd Medical Scientific Center
2. Pskov Regional Clinical Hospital
3. Volgograd State Medical University
Abstract
Relevance. Diagnosis of oral mucosa diseases is very difficult. Heterogeneity of the oral mucosa disease manifestation often requires invasive diagnostic methods, which cause the pain syndrome. Timely and complete pain syndrome relief and the impact on all phases of the w ound healing process allow faster patient rehabilitation. The study aimed to examine the effect of Ketanov MD and Cifran CT on the wound process and the pain syndrome intensity after incisional and excisional biopsies to verify the oral mucosa pathology. Materials and methods. The study surveyed 30 people with oral mucosal diseases. The patients (30 subjects) formed two groups: excisional (10 people) and incisional biopsy (20 people). In these groups, we clinically evaluated the course of the wound process, the pain syndrome intensity, oedema phenomena, hyperemia, and the exudate presence. We analysed the quality of life of such patients using a validated Russian v ersion of the questionnaire.Results. On the 3rd day after the biopsy, on top of the generally accepted treatment of oral mucosal diseases and Ketorol MD and Cifran CT intake, the patients noted moderate aching and discomfort when talking and eating. After 14 days, all patients showed an improvement in qualitative and quantitative parameters, the absence of pain and the development of reinfection on therapy with non-steroidal anti-inf lammatory and antibacterial drugs.Conclusion. These drugs have a positive effect on the course of the phases of the wound process. They help reduce the pain response and contribute to faster patient rehabilitation af ter the biopsies in oral mucosal diseases.
Publisher
Periodontal Association - RPA
Reference11 articles.
1. Makedonova YuA, Poroyskiy SV, Gavrikova LM, Afanaseva ОYu, Dyachenko SV, Aleksandrina ES. Comparative analysis of the effectiveness of the oral mucosa traumatic lesion treatment in patients with a comorbidity. Parodontologiya. 2021;26(3):229-233 (In Russ.). doi: 10.33925/1683-3759-2021-26-3-229-233
2. Lazzarotto B, Garcia C, Martinelli-Klay C, Lombardi T. Biopsy of the oral mucosa: Does size matter? Journal of stomatology, oral and maxillofacial surgery. 2022;15:S2468-7855(22)00036-21-5. doi: 10.1016/j.jormas.2022.02.005
3. Valdez JA, Brennan MT. Impact of Oral Cancer on Quality of Life. Dental clinics of North America. 2018;62(1):143-154. doi: 10.1016/j.cden.2017.09.001
4. Makedonova YuA, Afanasyeva OYu, Aleksandrina ES, Vargina SA. Formation of the principles of oncological alertness among dentists at an outpatient appointment. Cathedra - Кафедра. Dental education. 2021;76:46-49 (In Russ.). Available from: https://elibrary.ru/item.asp?id=47758353
5. Maymone MBC, Greer RO, Kesecker J, Sahitya PC, Burdine LK, Cheng AD, et al. Premalignant and malignant oral mucosal lesions: Clinical and pathological findings. Journal of the American Academy of Dermatology. 2019;81(1):59-71. doi: 10.1016/j.jaad.2018.09.060