Enantiomeric Separation of (R)-5-(1-Hydroxyethyl)-2-(pyridine- 2-yl)-[1, 3, 4]-thiadiazole, an Intermediate of Nafithromycin on Immobilized Amylose Based Stationary Phase

Author:

Jadhav Rajiv A.1,Ahirrao Vinod K.1,Patil Rushikesh H.1,More Kiran B.1,Tile Anil R.1,Rane Vipul P.1,Sonawane Pravin S.1,Yeole Ravindra D.1

Affiliation:

1. Wockhardt Research Centre, D-4, MIDC, Chikalthana, Aurangabad, 431006, India

Publisher

Informa UK Limited

Subject

General Medicine

Reference23 articles.

1. https://www.fda.gov/Drugs%20/Guidnce%20ComplianceRegulatoryInformation/Guidances/ucm1/22883.html, 1992.

2. Trivedi, B., Deshpande, P., Ravikumar, T., Gupta, S., Diwakar, S., Pawar, S., Patil, V., Dekhane, D., Patel, M., Bhavsar, S., Mishra, A., Solanki, M., Jafri, M., Bhagwat, S. (2012). US Patent WO 2012/076989 A1. Ketolide compounds.

3. Enantiomeric Separation and Thermodynamic investigation of (R)-5-[1-(4-Nitrobenzylsulfonyloxy)-ethyl]-5-(pyridine-2-yl)- [1,3,4]-thiadiazole, a Key Intermediate of Nafithromycin

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