Human Mesenchymal glioblastomas are characterized by an increased immune cell presence compared to Proneural and Classical tumors

Author:

Kaffes Ioannis12,Szulzewsky Frank3,Chen Zhihong14ORCID,Herting Cameron J.1,Gabanic Ben1,Velázquez Vega José E.5,Shelton Jennifer5,Switchenko Jeffrey M.6,Ross James L.1,McSwain Leon F.1,Huse Jason T.7,Westermark Bengt8,Nelander Sven8,Forsberg-Nilsson Karin8,Uhrbom Lene8,Maturi Naga Prathyusha8,Cimino Patrick. J.39,Holland Eric C.3,Kettenmann Helmut2,Brennan Cameron W.10,Brat Daniel J.11,Hambardzumyan Dolores14ORCID

Affiliation:

1. Department of Pediatrics, Aflac Cancer and Blood Disorders Center, Children’s Healthcare of Atlanta, Winship Cancer Institute, Emory University School of Medicine, Atlanta, GA, USA

2. Department of Cellular Neurosciences, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany

3. Department of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA

4. Discovery and Developmental Therapeutics Program, Winship Cancer Institute, Emory University, Atlanta, GA, USA

5. Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA

6. Department of Biostatistics and Bioinformatics, Winship Cancer Institute, Emory University, Atlanta, GA, USA

7. Departments of Pathology and Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

8. Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden

9. Department of Pathology, University of Washington, Seattle, WA, USA

10. Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York City, NY, USA

11. Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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