Immune-checkpoint blockade of CTLA-4 (CD152) in antigen-specific human T-cell responses differs profoundly between neonates, children, and adults

Author:

Arra Aditya12,Pech Maximilian12,Fu Hang12,Lingel Holger12,Braun Franziska12,Beyer Christian3,Spiliopoulou Myra3,Bröker Barbara M.4,Lampe Karen5,Arens Christoph25,Vogel Katrin12,Pierau Mandy12,Brunner-Weinzierl Monika C.12

Affiliation:

1. Department of Experimental Pediatrics and Neonatology, Otto-von-Guericke-University, Magdeburg, Germany

2. Health Campus Immunology, Infectiology and Inflammation, Otto-von-Guericke-University, Magdeburg, Germany

3. Department of Informatics, Otto-von-Guericke-University, Magdeburg, Germany

4. Department of Immunology, Institute of Immunology and Transfusion Medicine, University Medicine Greifswald, Greifswald, Germany

5. Department of Otorhinolaryngology, Head and Neck Surgery, Otto-von-Guericke-University, Magdeburg, Germany

Funder

European Regional Development Fund

Deutsche Forschungsgemeinschaft

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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