Reprogramming the immunosuppressive tumor microenvironment results in successful clearance of tumors resistant to radiation therapy and anti-PD-1/PD-L1

Author:

Mukherjee Debayan1,Romano Erminia1,Walshaw Richard1,Zeef Leo A. H.2,Banyard Antonia3,Kitcatt Stephen J.4,Cheadle Eleanor J.1,Tuomela Karoliina1,Pendharkar Swati1,Al-Deka Aws1,Salerno Beatrice1,Raby Sophie1,Mills Ian G.56,Honeychurch Jamie1,Illidge Tim M.1

Affiliation:

1. Targeted Therapy Group, Division of Cancer Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, UK

2. Bioinformatics Core Facility, Michael Smith Building, The University of Manchester, Manchester, UK

3. Mass and Flow Cytometry Core Facility, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK

4. Scientific Computing Core Facility, Cancer Research UK Manchester Institute, The University of Manchester, Manchester, UK

5. Nuffield Department of Surgical Sciences, John Radcliffe Hospital, University of Oxford, Oxford, UK

6. Patrick G. Johnston Centre for Cancer Research, Queen’s University of Belfast, Belfast, UK

Funder

CRUK Programme

Belfast-Manchester Movember Centre for Excellence

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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