An experimental model of anti-PD-1 resistance exhibits activation of TGFß and Notch pathways and is sensitive to local mRNA immunotherapy-Reference-Cited by-同舟云学术

An experimental model of anti-PD-1 resistance exhibits activation of TGFß and Notch pathways and is sensitive to local mRNA immunotherapy

Published:2021-01-01 Issue:1 Volume:10 Page:
ISSN:2162-402X
Container-title:OncoImmunology
language:en
Short-container-title:OncoImmunology

Author:

Bernardo Marie¹,Tolstykh Tatiana¹,Zhang Yu-an¹,Bangari Dinesh S.¹,Cao Hui¹,Heyl Kerstin A.²,Lee Joon Sang¹,Malkova Natalia V.¹,Malley Katie¹,Marquez Eladio¹,Pollard Jack¹,Qu Hui¹,Roberts Errin¹,Ryan Sue¹,Singh Kuldeep¹,Sun Fangxian¹,Wang Emma¹,Bahjat Keith¹,Wiederschain Dmitri¹,Wagenaar Timothy R.¹

Affiliation:

1. Sanofi Research and Development, Cambridge, MA, USA

2. Preclinical Research and Immunotherapies, BioNTech SE, Mainz, Germany

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

Link

https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2021.1881268

Reference41 articles.

1. PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?

2. Regulation and Function of the PD-L1 Checkpoint