Preclinical immunoPET/CT imaging using Zr-89-labeled anti-PD-L1 monoclonal antibody for assessing radiation-induced PD-L1 upregulation in head and neck cancer and melanoma

Author:

Kikuchi Masahiro12,Clump David A.23,Srivastava Raghvendra M.2,Sun Lingyi4,Zeng Dexing4,Diaz-Perez Julio A.56ORCID,Anderson Carolyn J.4789ORCID,Edwards W. Barry7,Ferris Robert L.23101112

Affiliation:

1. Department of Otolaryngology-Head and Neck Surgery, Kobe City Medical Center General Hospital, Kobe, Japan

2. Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA

3. Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA, USA

4. Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA

5. Department of Dermatology, University of Pittsburgh, Pittsburgh, PA, USA

6. Translational Medicine Program, CEINDO, Madrid, Spain

7. Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USA

8. Department of Pharmacology & Chemical Biology, University of Pittsburgh, Pittsburgh, PA, USA

9. Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA, USA

10. Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA

11. Cancer Immunology Program, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA

12. Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA

Publisher

Informa UK Limited

Subject

Oncology,Immunology,Immunology and Allergy

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