Phase I trial of anti-GD2 monoclonal antibody hu3F8 plus GM-CSF: Impact of body weight, immunogenicity and anti-GD2 response on pharmacokinetics and survival
Author:
Affiliation:
1. ScD, Memorial Sloan Kettering Cancer Center, Department of Pediatrics, 1275 York Avenue, New York, NY, USA
2. Department of Pediatrics, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, USA
Publisher
Informa UK Limited
Subject
Oncology,Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/2162402X.2017.1358331
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1. GD2-Targeted Immunotherapy and Radioimmunotherapy
2. Anti-GD2 Antibody with GM-CSF, Interleukin-2, and Isotretinoin for Neuroblastoma
3. Ch14.18 antibody produced in CHO cells in relapsed or refractory Stage 4 neuroblastoma patients
4. Pharmacokinetics and pharmacodynamics of ch14.18/CHO in relapsed/refractory high-risk neuroblastoma patients treated by long-term infusion in combination with IL-2
5. Murine Anti-GD2 Monoclonal Antibody 3F8 Combined With Granulocyte-Macrophage Colony-Stimulating Factor and 13-Cis-Retinoic Acid in High-Risk Patients With Stage 4 Neuroblastoma in First Remission
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