Strategies to identify, engineer, and validate antibodies targeting blood–brain barrier receptor-mediated transcytosis systems for CNS drug delivery
Author:
Affiliation:
1. Department of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA
2. Department of Neurological Surgery, University of Wisconsin-Madison, Madison, WI, USA
Funder
National Institutes of Health
Publisher
Informa UK Limited
Subject
Pharmaceutical Science
Link
https://www.tandfonline.com/doi/pdf/10.1080/17425247.2023.2286371
Reference76 articles.
1. Brain Bioavailability of Human Intravenous Immunoglobulin and its Transport through the Murine Blood–Brain Barrier
2. Late-Stage Failures of Monoclonal Antibody Drugs: A Retrospective Case Study Analysis
3. Treatment of Alzheimer’s Disease and Blood–Brain Barrier Drug Delivery
4. The transferrin receptor: role in health and disease
5. Physiological blood–brain transport is impaired with age by a shift in transcytosis
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