An update on pharmacogenetic factors influencing the metabolism and toxicity of artemisinin-based combination therapy in the treatment of malaria

Author:

Pernaute-Lau Leyre12,Camara Mahamadou3,Nóbrega de Sousa Taís4,Morris Ulrika1,Ferreira Marcelo Urbano25,Gil José Pedro126

Affiliation:

1. Department of Microbiology, Tumor and Cell biology, Karolinska Institutet, Solna, Sweden

2. Faculty of Sciences, BioISI - Biosystems & Integrative Sciences Institute, University of Lisbon, Lisbon, 1749-016, Portugal

3. Department of Epidemiology of Parasitic Diseases, Faculty of Pharmacy, Malaria Research and Training Center, University of Science, Techniques and Technologies of Bamako, Bamako, Mali

4. Molecular Biology and Malaria Immunology Research Group, Instituto René Rachou, Fundação Oswaldo Cruz (FIOCRUZ), Belo Horizonte, Brasil

5. Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

6. Global Health and Tropical Medicine, Institute of Hygiene and Tropical Medicine, Nova University of Lisbon, Portugal

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

European and Developing Countries Clinical Trials Partnership

Fundação de Amparo *a Pesquisa do Estado de mInas Gerais

Fundação para a Ciência e Tecnologia

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Reference255 articles.

1. The pharmacogenetics of antimalaria artemisinin combination therapy

2. MMV-supported projects [Internet]. Geneva: Medicines for Malaria Venture; [cited 2021 Jun 08]. Available from: https://www.mmv.org/research-development/mmv-supported-projects

3. Mefloquine resistance in Plasmodium falciparum and increased pfmdr1 gene copy number

4. Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya

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