Toxic metabolites and metabolic soft spots of celastrol based on glutathione metabolic capture and high-resolution mass spectrometry-Reference-Cited by-同舟云学术

Toxic metabolites and metabolic soft spots of celastrol based on glutathione metabolic capture and high-resolution mass spectrometry

Published:2023-12-02 Issue:12 Volume:19 Page:1023-1032
ISSN:1742-5255
Container-title:Expert Opinion on Drug Metabolism & Toxicology
language:en
Short-container-title:Expert Opinion on Drug Metabolism & Toxicology

Author:

Jiang Xiaojuan¹,Yuan Caixia¹,Ding Rong¹,Lu Di¹,Peng Xiaoyu¹,Dong Zhihao¹,Zhu Chunyan¹,Lin Yihua²³,Wu Caisheng¹,Xie Qiang⁴

Affiliation:

1. Fujian Provincial Key Laboratory of Innovative Drug Target Research and State Key Laboratory of Cell Stress Biology, School of Pharmaceutical Sciences, Xiamen University, Xiamen, China

2. Department of Respiratory and Critical Care Medicine, The Third Clinical Medical College, Fujian Medical University, Fuzhou, China

3. Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xiamen University, Xiamen, China

4. Department of Cardiology, The First Affiliated Hospital of Xiamen University, Xiamen, China

Funder

National Natural Science Foundation of China

Fujian Province Science and Technology Project

Fundamental Research Funds for the Chinese Central Universities

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/17425255.2023.2294042

Reference24 articles.

1. Biosynthesis, total synthesis, structural modifications, bioactivity, and mechanism of action of the quinone‐methide triterpenoid celastrol

2. Molecular Understanding and Modern Application of Traditional Medicines: Triumphs and Trials

3. Tripterygium wilfordii : An inspiring resource for rheumatoid arthritis treatment

4. Celastrol suppresses obesity process via increasing antioxidant capacity and improving lipid metabolism

5. Celastrol targeting Nedd4 reduces Nrf2-mediated oxidative stress in astrocytes after ischemic stroke