What is the significance of the pharmacokinetic profile and potential drug–drug interactions of long-acting intramuscular cabotegravir and rilpivirine?

Author:

Bettonte Sara12,Berton Mattia12,Marzolini Catia123

Affiliation:

1. Division of Infectious Diseases and Hospital Epidemiology, Departments of Medicine and Clinical Research, University Hospital, Basel, Switzerland

2. Faculty of Medicine, University of Basel, Basel, Switzerland

3. Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK

Funder

Swiss National Foundation

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Reference20 articles.

1. US. Food and drug administration. Cabenuva product label. 2023 Mar. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/212888s005s006lbl.pdf

2. European Medicines Agency. Rekambys summary of product characteristics. 2023 Mar. Available from: https://www.ema.europa.eu/en/documents/product-information/rekambys-epar-product-information_en.pdf

3. European Medicines Agency. Vocabria summary of product characteristics. 2023 Mar. Available from: https://www.ema.europa.eu/en/documents/product-information/vocabria-epar-product-information_en.pdf

4. Multiparametric magnetic resonance imaging to characterize cabotegravir long‐acting formulation depot kinetics in healthy adult volunteers

5. Pharmacokinetics and Drug–Drug Interactions of Long-Acting Intramuscular Cabotegravir and Rilpivirine

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