Predictors of tacrolimus pharmacokinetic variability: current evidences and future perspectives

Author:

Degraeve Alexandra L12,Moudio Serge13,Haufroid Vincent34,Chaib Eddour Djamila5,Mourad Michel5,Bindels Laure B2,Elens Laure13

Affiliation:

1. Integrated Pharmacometrics, Pharmacogenomics and Pharmacokinetics (PMGK), Louvain Drug Research Institute (LDRI), Université Catholique De Louvain, Brussels, Belgium

2. Metabolism and Nutrition Research Group (Mnut), Louvain Drug Research Institute (LDRI), Université Catholique De Louvain, Brussels, Belgium

3. Louvain Centre for Toxicology and Applied Pharmacology (LTAP), Institut De Recherche Expérimentale Et Clinique (IREC), Université Catholique De Louvain, Brussels, Belgium

4. Department of Clinical Chemistry, Cliniques Universitaires Saint-Luc, Brussels, Belgium

5. Kidney and Pancreas Transplantation Unit, Cliniques Universitaires Saint-Luc, Brussels, Belgium

Funder

Fonds de la Recherche Scientifique

Publisher

Informa UK Limited

Subject

Pharmacology,Toxicology,General Medicine

Reference207 articles.

1. Transplant-observatory.org [Internet]. Madrid: global Observatory on Donation and Transplantation; 2018 [cited 2020 Apr 4]. Available from: http://www.transplant-observatory.org/data-charts-and-tables/Those2018 data are based on the Global Observatory on Donation and Transplantation (GODT) data, produced by the WHO-ONT collaboration.

2. Overview of Immunosuppressive Therapy in Solid Organ Transplantation

3. OPTN / SRTR 2018 Annual Data Report: Kidney

4. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

5. Tacrolimus (FK506)-Associated Renal Pathology

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