PK/PD evaluation of fimasartan for the treatment of hypertension Current evidences and future perspectives
Author:
Affiliation:
1. Department of Cardiology and Cardiovascular Pathophysiology, Hospital and University of Perugia, Perugia, Italy
2. Department of Internal Medicine, Hospital of Assisi, Assisi, Italy
3. Department of Medicine, University of Perugia, Perugia, Italy
Funder
not funded
Publisher
Informa UK Limited
Subject
Pharmacology,Toxicology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/17425255.2018.1468435
Reference53 articles.
1. Angiotensin II receptor antagonists
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3. Physiology of Local Renin-Angiotensin Systems
4. The role of the renin-angiotensin system in the development of cardiovascular disease
5. Angio-oedema and urticaria associated with angiotensin converting enzyme inhibitors.
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1. Fimasartan attenuates edema and systemic changes in egg albumin-induced paw inflammation in rats;Journal of Advanced Pharmacy Education and Research;2023
2. Pharmacokinetic comparison between a fixed-dose combination of fimasartan/amlodipine/hydrochlorothiazide 60/10/25 mg and a corresponding loose combination of fimasartan/amlodipine 60/25 mg and hydrochlorothiazide 25 mg in healthy subjects;Translational and Clinical Pharmacology;2021
3. Fimasartan reduces neointimal formation and inflammation after carotid arterial injury in apolipoprotein E knockout mice;Molecular Medicine;2019-07-15
4. Discovery of the bifunctional modulator of angiotensin II type 1 receptor (AT1R) and PPARγ derived from the AT1R antagonist, Fimasartan;Bioorganic & Medicinal Chemistry Letters;2018-10
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